| Group A | 17/09/2022 | Jocoro FC | - | Dragón | 1:0 | ||||
| Group A | 21/09/2022 | Dragón | - | AD Chalatenango | 0:1 | ||||
| Group A | 25/09/2022 | Luis Ángel Firpo | - | Dragón | 1:2 | ||||
| Group A | 28/09/2022 | Platense Zacatecoluca | - | Dragón | 0:0 | ||||
| Group A | 02/10/2022 | Dragón | - | CD Águila | 1:1 |  |
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| Group A | 08/10/2022 | Dragón | - | Jocoro FC | 1:0 |  |
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| Group A | 13/10/2022 | AD Chalatenango | - | Dragón | 1:2 | |
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| Group A | 16/10/2022 | Dragón | - | Luis Ángel Firpo | 1:0 | |
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| Group A | 19/10/2022 | Dragón | - | Platense Zacatecoluca | 1:0 | ||||
| Group A | 23/10/2022 | CD Águila | - | Dragón | 2:2 | |
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| Quarter-finals | 26/10/2022 | Dragón | - | FAS | 3:2 | |
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| Quarter-finals | 30/10/2022 | FAS | - | Dragón | 3:1 |
El Salvador