| 1. Round | 13/01/2021 | Municipal Grecia | - | Deportivo Saprissa | 0:0 | ||||
| 2. Round | 17/01/2021 | Municipal Grecia | - | Sporting FC | 1:1 | ||||
| 4. Round | 24/01/2021 | Municipal Grecia | - | Municipal Pérez Zeledón | 0:0 | ||||
| 7. Round | 06/02/2021 | Municipal Grecia | - | Jicaral | 2:0 |  |
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| 6. Round | 11/02/2021 | LD Alajuelense | - | Municipal Grecia | 3:0 | ||||
| 8. Round | 15/02/2021 | AD San Carlos | - | Municipal Grecia | 1:4 | ||||
| 9. Round | 21/02/2021 | Guadalupe | - | Municipal Grecia | 1:1 | ||||
| 14. Round | 20/03/2021 | Municipal Grecia | - | CS Herediano | 1:4 | |
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| 16. Round | 03/04/2021 | Municipal Grecia | - | Limón FC | 2:2 | ||||
| 17. Round | 09/04/2021 | Municipal Grecia | - | LD Alajuelense | 1:4 | ||||
| 19. Round | 22/04/2021 | Municipal Grecia | - | AD San Carlos | 2:1 |  |
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| 20. Round | 25/04/2021 | Municipal Grecia | - | Guadalupe | 0:0 | ||||
| 21. Round | 01/05/2021 | CS Cartaginés | - | Municipal Grecia | 2:0 |
Costa Rica