| 12. Round | 18/09/2021 | Jicaral | - | Municipal Pérez Zeledón | 3:0 | ||||
| 13. Round | 26/09/2021 | CS Herediano | - | Jicaral | 1:0 | ||||
| 15. Round | 12/10/2021 | Sporting FC | - | Jicaral | 2:1 | ||||
| 16. Round | 17/10/2021 | Jicaral | - | AD San Carlos | 0:4 | ||||
| 17. Round | 24/10/2021 | Santos de Guápiles | - | Jicaral | 2:3 | ||||
| 18. Round | 27/10/2021 | Jicaral | - | Deportivo Saprissa | 0:0 | ||||
| 19. Round | 30/10/2021 | Guadalupe | - | Jicaral | 2:0 |  |
Costa Rica