| 1. Round | 09/08/2020 | KV Kortrijk | - | Waasland-Beveren | 1:3 | ||||
| 2. Round | 17/08/2020 | Waasland-Beveren | - | Standard Liège | 1:2 |  |
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| 3. Round | 22/08/2020 | SV Zulte Waregem | - | Waasland-Beveren | 4:1 | ||||
| 4. Round | 29/08/2020 | Waasland-Beveren | - | Oud-Heverlee Leuven | 1:3 | ||||
| 5. Round | 12/09/2020 | Club Brugge KV | - | Waasland-Beveren | 4:1 | ||||
| 7. Round | 26/09/2020 | K Beerschot VA | - | Waasland-Beveren | 3:2 | ||||
| 17. Round | 20/12/2020 | Waasland-Beveren | - | Royal Antwerp FC | 0:3 | ||||
| 19. Round | 27/12/2020 | KRC Genk | - | Waasland-Beveren | 1:1 | ||||
| 30. Round | 11/01/2021 | Standard Liège | - | Waasland-Beveren | 3:1 | ||||
| 20. Round | 16/01/2021 | Waasland-Beveren | - | SV Zulte Waregem | 1:5 | ||||
| 32. Round | 03/04/2021 | KV Oostende | - | Waasland-Beveren | 0:2 | ||||
| 31. Round | 06/04/2021 | Waasland-Beveren | - | Sint-Truidense VV | 2:4 | ||||
| 33. Round | 11/04/2021 | Waasland-Beveren | - | KV Kortrijk | 3:4 | ||||
| 34. Round | 18/04/2021 | Oud-Heverlee Leuven | - | Waasland-Beveren | 1:2 |
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