| 1. Round | 23/07/2022 | Sporting Charleroi | - | KAS Eupen | 3:1 |  |
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| 2. Round | 31/07/2022 | KAS Eupen | - | Club Brugge KV | 2:1 | ||||
| 3. Round | 06/08/2022 | KRC Genk | - | KAS Eupen | 4:2 | ||||
| 4. Round | 14/08/2022 | KAS Eupen | - | Royal Antwerp FC | 0:1 | ||||
| 5. Round | 19/08/2022 | KAS Eupen | - | RFC Seraing | 1:3 | |
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| 7. Round | 03/09/2022 | KAS Eupen | - | KV Kortrijk | 0:1 | ||||
| 8. Round | 10/09/2022 | KV Oostende | - | KAS Eupen | 1:0 | |
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| 11. Round | 09/10/2022 | KAS Eupen | - | KAA Gent | 0:4 | ||||
| 15. Round | 30/10/2022 | RSC Anderlecht | - | KAS Eupen | 4:2 | ||||
| 16. Round | 05/11/2022 | KAS Eupen | - | Standard Liège | 2:0 |  |
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| 20. Round | 14/01/2023 | KAS Eupen | - | Sint-Truidense VV | 0:2 | ||||
| 21. Round | 17/01/2023 | Oud-Heverlee Leuven | - | KAS Eupen | 1:1 | ||||
| 23. Round | 27/01/2023 | Standard Liège | - | KAS Eupen | 3:1 | ||||
| 22. Round | 01/02/2023 | KAS Eupen | - | KRC Genk | 1:1 | ||||
| 24. Round | 04/02/2023 | KAS Eupen | - | KVC Westerlo | 1:1 | ||||
| 25. Round | 10/02/2023 | KAS Eupen | - | KV Mechelen | 2:1 |
Belgium