| 4. Round | 27/02/2022 | Sport Boys | - | Carlos Stein | 2:1 | ||||
| 5. Round | 06/03/2022 | Universidad Cesar Vallejo | - | Sport Boys | 1:1 | ||||
| 6. Round | 13/03/2022 | Sport Boys | - | Deportivo Municipal | 1:2 |  |
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| 7. Round | 19/03/2022 | Cienciano | - | Sport Boys | 4:1 | ||||
| 8. Round | 02/04/2022 | Sport Boys | - | Deportivo Binacional | 1:3 | ||||
| 9. Round | 10/04/2022 | AD Tarma | - | Sport Boys | 3:0 | ||||
| 10. Round | 17/04/2022 | Sport Boys | - | Ayacucho FC | 1:0 | ||||
| 11. Round | 24/04/2022 | Universitario de Deportes | - | Sport Boys | 1:1 | ||||
| 12. Round | 02/05/2022 | Academia Cantolao | - | Sport Boys | 0:1 |  |
Peru