| 2. Round | 01/09/2021 | KRC Genk [U18] | - | Royal Antwerp FC [U18] | 4:2 | ||||
| 3. Round | 04/09/2021 | Royal Antwerp FC [U18] | - | Cercle Brugge [U18] | 1:0 | ||||
| 8. Round | 01/12/2021 | Royal Antwerp FC [U18] | - | RSC Anderlecht [U18] | 1:2 | ||||
| 15. Round | 15/01/2022 | Royal Antwerp FC [U18] | - | KRC Genk [U18] | 2:1 | ||||
| 17. Round | 29/01/2022 | Sint-Truidense VV [U18] | - | Royal Antwerp FC [U18] | 1:0 | ||||
| 19. Round | 12/02/2022 | RSC Anderlecht [U18] | - | Royal Antwerp FC [U18] | 1:3 | ||||
| 20. Round | 19/02/2022 | Royal Antwerp FC [U18] | - | KVC Westerlo [U18] | 3:1 | ||||
| 21. Round | 05/03/2022 | Standard Liège [U18] | - | Royal Antwerp FC [U18] | 6:0 | ||||
| 22. Round | 12/03/2022 | Royal Antwerp FC [U18] | - | KV Mechelen [U18] | 3:1 | ||||
| 24. Round | 26/03/2022 | Royal Antwerp FC [U18] | - | SV Zulte Waregem [U18] | 0:2 | ||||
| 25. Round | 02/04/2022 | KAA Gent [U18] | - | Royal Antwerp FC [U18] | 4:0 | ||||
| 26. Round | 23/04/2022 | Royal Antwerp FC [U18] | - | Sporting Charleroi [U18] | 4:0 |
Belgium