| 1. Round | 19/03/2021 | Shamrock Rovers | - | St Patrick's Athletic | 1:1 | ||||
| 8. Round | 30/04/2021 | Finn Harps | - | Shamrock Rovers | 0:2 | ||||
| 10. Round | 08/05/2021 | St Patrick's Athletic | - | Shamrock Rovers | 1:2 | ||||
| 12. Round | 21/05/2021 | Dundalk FC | - | Shamrock Rovers | 2:1 |  |
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| 13. Round | 24/05/2021 | Shamrock Rovers | - | Sligo Rovers | 0:1 | ||||
| 19. Round | 02/07/2021 | Shamrock Rovers | - | Dundalk FC | 3:1 | ||||
| 22. Round | 30/07/2021 | Shamrock Rovers | - | St Patrick's Athletic | 3:1 | ||||
| 26. Round | 03/09/2021 | Finn Harps | - | Shamrock Rovers | 2:1 | ||||
| 32. Round | 23/10/2021 | Longford Town | - | Shamrock Rovers | 0:1 | ||||
| 33. Round | 29/10/2021 | Shamrock Rovers | - | Finn Harps | 3:0 | ||||
| 35. Round | 12/11/2021 | Bohemian FC | - | Shamrock Rovers | 3:1 | ||||
| 36. Round | 19/11/2021 | Shamrock Rovers | - | Drogheda United | 2:1 |
Ireland
