| 1. Round | 21/07/2022 | CS Cartaginés | - | Municipal Grecia | 1:2 |  |
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| 2. Round | 24/07/2022 | Municipal Grecia | - | Deportivo Saprissa | 0:3 | ||||
| 3. Round | 31/07/2022 | Municipal Pérez Zeledón | - | Municipal Grecia | 2:3 | |
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| 5. Round | 12/08/2022 | Puntarenas FC | - | Municipal Grecia | 3:1 | ||||
| 6. Round | 14/08/2022 | Municipal Grecia | - | CS Cartaginés | 3:5 | ||||
| 7. Round | 21/08/2022 | AD San Carlos | - | Municipal Grecia | 1:2 | ||||
| 8. Round | 27/08/2022 | Municipal Grecia | - | Puntarenas FC | 1:0 | ||||
| 9. Round | 01/09/2022 | Deportivo Saprissa | - | Municipal Grecia | 4:0 | ||||
| 10. Round | 05/09/2022 | Municipal Grecia | - | Municipal Pérez Zeledón | 2:3 | ||||
| 11. Round | 12/09/2022 | Santos de Guápiles | - | Municipal Grecia | 5:3 | ||||
| 12. Round | 17/09/2022 | Municipal Grecia | - | Sporting FC | 2:0 | ||||
| 13. Round | 21/09/2022 | Municipal Grecia | - | AD Guanacasteca | 4:1 | |
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| 14. Round | 25/09/2022 | Guadalupe | - | Municipal Grecia | 0:1 | |
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| 15. Round | 27/09/2022 | Municipal Grecia | - | CS Herediano | 1:2 | ||||
| 16. Round | 02/10/2022 | LD Alajuelense | - | Municipal Grecia | 4:3 |
Costa Rica