| 5. Round | 09/09/2000 | KV Mechelen | - | Standard Liège | 0:4 | ||||
| 6. Round | 16/09/2000 | RAA La Louviére | - | KV Mechelen | 2:2 | ||||
| 7. Round | 23/09/2000 | KV Mechelen | - | Germinal Beerschot | 2:3 | ||||
| 8. Round | 01/10/2000 | Club Brugge KV | - | KV Mechelen | 5:2 | ||||
| 11. Round | 28/10/2000 | Sint-Truidense VV | - | KV Mechelen | 1:0 |
Belgium