| 3. Round | 05/02/2022 | Tigres FC | - | Atlético FC | 1:1 | ||||
| 5. Round | 18/02/2022 | Tigres FC | - | Bogotá FC | 3:0 | ||||
| 6. Round | 26/02/2022 | Orsomarso SC | - | Tigres FC | 0:2 | ||||
| 8. Round | 10/03/2022 | Deportes Quindío | - | Tigres FC | 0:0 | ||||
| 10. Round | 26/03/2022 | Boca Juniors de Cali | - | Tigres FC | 2:0 |
Colombia