| 1. Round | 18/01/2025 | Rancho Santana | - | Real Estelí FC | 3:2 | ||||
| 2. Round | 22/01/2025 | Rancho Santana | - | ART Municipal Jalapa | 4:0 | ||||
| 3. Round | 26/01/2025 | Managua FC | - | Rancho Santana | 1:0 | ||||
| 5. Round | 03/02/2025 | Rancho Santana | - | UNAN Managua | 0:0 | ||||
| 6. Round | 09/02/2025 | Rancho Santana | - | Club Deportivo Ocotal | 3:1 | ||||
| 7. Round | 17/02/2025 | CD Walter Ferretti | - | Rancho Santana | 0:0 |  |
|||
| 8. Round | 21/02/2025 | Rancho Santana | - | Diriangén FC | 0:1 | ||||
| 9. Round | 23/02/2025 | H&H Export Sébaco | - | Rancho Santana | 1:0 | ||||
| 4. Round | 26/02/2025 | Matagalpa FC | - | Rancho Santana | 2:1 | |
|||
| 10. Round | 02/03/2025 | Real Estelí FC | - | Rancho Santana | 3:0 | ||||
| 11. Round | 09/03/2025 | ART Municipal Jalapa | - | Rancho Santana | 2:0 |  |
|||
| 15. Round | 07/04/2025 | Club Deportivo Ocotal | - | Rancho Santana | 2:0 | ||||
| 17. Round | 28/04/2025 | Diriangén FC | - | Rancho Santana | 3:0 | ||||
| 18. Round | 01/05/2025 | Rancho Santana | - | H&H Export Sébaco | 1:1 |
Ecuador