| 1. Round | 20/11/2021 | Perth Glory | - | Adelaide United | 1:1 | ||||
| 2. Round | 26/11/2021 | Western United | - | Perth Glory | 1:0 | ||||
| 3. Round | 05/12/2021 | Melbourne Victory | - | Perth Glory | 0:3 | ||||
| 4. Round | 08/12/2021 | Melbourne City FC | - | Perth Glory | 1:0 |  |
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| 5. Round | 19/01/2022 | Brisbane Roar | - | Perth Glory | 1:0 | ||||
| 9. Round | 02/02/2022 | Western Sydney Wanderers | - | Perth Glory | 1:0 | ||||
| 16. Round | 27/02/2022 | Perth Glory | - | Western United | 0:2 | ||||
| 13. Round | 02/03/2022 | Melbourne City FC | - | Perth Glory | 2:2 | ||||
| 17. Round | 06/03/2022 | Perth Glory | - | Adelaide United | 1:2 | ||||
| 18. Round | 15/03/2022 | Perth Glory | - | Central Coast Mariners | 0:0 | ||||
| 19. Round | 19/03/2022 | Perth Glory | - | Brisbane Roar | 1:4 | ||||
| 20. Round | 26/03/2022 | Wellington Phoenix | - | Perth Glory | 2:1 | ||||
| 8. Round | 03/04/2022 | Macarthur FC | - | Perth Glory | 4:2 | |
Australia