| 1. Round | 17/07/2021 | Universidad San Martín | - | Mannucci | 0:2 | ||||
| 3. Round | 30/07/2021 | Universidad San Martín | - | Cienciano | 1:1 | ||||
| 2. Round | 03/09/2021 | Sporting Cristal | - | Universidad San Martín | 1:1 | ||||
| 10. Round | 13/09/2021 | Universidad San Martín | - | Universitario de Deportes | 0:2 |  |
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| 14. Round | 03/10/2021 | Universidad San Martín | - | Cusco FC | 1:1 |
Venezuela