| 1. Round | 13/08/2021 | AC Bellinzona | - | BSC Young Boys II | 2:0 | ||||
| 6. Round | 11/09/2021 | FC Sion II | - | BSC Young Boys II | 2:0 | ||||
| 7. Round | 22/09/2021 | BSC Young Boys II | - | Etoile Carouge FC | 1:5 | ||||
| 8. Round | 25/09/2021 | FC Zürich II | - | BSC Young Boys II | 2:2 | ||||
| 9. Round | 02/10/2021 | BSC Young Boys II | - | FC Breitenrain Bern | 3:3 | ||||
| 10. Round | 09/10/2021 | SC Brühl | - | BSC Young Boys II | 0:3 | ||||
| 11. Round | 16/10/2021 | BSC Young Boys II | - | SC YF/Juventus Zürich | 1:1 | ||||
| 13. Round | 30/10/2021 | BSC Young Boys II | - | FC Black Stars Basel | 4:3 |  |
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| 14. Round | 06/11/2021 | FC Bavois | - | BSC Young Boys II | 2:1 | ||||
| 15. Round | 13/11/2021 | BSC Young Boys II | - | FC Stade Nyonnais | 2:0 | ||||
| 16. Round | 20/11/2021 | BSC Young Boys II | - | AC Bellinzona | 1:1 | |
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| 21. Round | 06/03/2022 | BSC Young Boys II | - | FC Sion II | 3:0 | ||||
| 22. Round | 12/03/2022 | Etoile Carouge FC | - | BSC Young Boys II | 2:0 |
Switzerland