| 2. Round | 26/01/2019 | Club Olimpia | - | San Lorenzo | 2:0 | ||||
| 3. Round | 03/02/2019 | Sportivo Luqueño | - | Club Olimpia | 1:5 | ||||
| 5. Round | 09/02/2019 | Sol de América | - | Club Olimpia | 0:1 |  |
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| 1. Round | 13/02/2019 | Club Nacional | - | Club Olimpia | 2:4 | ||||
| 6. Round | 17/02/2019 | Club Olimpia | - | Cerro Porteño | 2:2 | ||||
| 7. Round | 24/02/2019 | Libertad | - | Club Olimpia | 2:3 | ||||
| 13. Round | 30/03/2019 | San Lorenzo | - | Club Olimpia | 1:4 |  |
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| 18. Round | 28/04/2019 | Club Olimpia | - | Libertad | 3:0 | ||||
| 19. Round | 01/05/2019 | Deportivo Capiatá | - | Club Olimpia | 2:2 | |
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| 21. Round | 14/05/2019 | River Plate | - | Club Olimpia | 2:2 |
Colombia