| 1. Round | 09/07/2022 | Ayacucho FC | - | Deportivo Municipal | 1:1 | ||||
| 2. Round | 17/07/2022 | Carlos Stein | - | Ayacucho FC | 2:2 | ||||
| 3. Round | 22/07/2022 | Ayacucho FC | - | Universidad Cesar Vallejo | 0:1 | ||||
| 6. Round | 06/08/2022 | Deportivo Binacional | - | Ayacucho FC | 4:1 |  |
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| 7. Round | 13/08/2022 | Ayacucho FC | - | AD Tarma | 1:2 | ||||
| 13. Round | 01/10/2022 | Mannucci | - | Ayacucho FC | 0:1 | |
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| 17. Round | 19/10/2022 | Sport Huancayo | - | Ayacucho FC | 0:1 | ||||
| 18. Round | 25/10/2022 | Ayacucho FC | - | Alianza Lima | 0:1 | ||||
| 19. Round | 29/10/2022 | Academia Cantolao | - | Ayacucho FC | 1:1 |
Peru