| Group A | 06/11/2022 | Millonarios | - | Santa Fe | 1:1 |  |
|||
| Group A | 09/11/2022 | Santa Fe | - | Deportivo Pereira | 2:0 | ||||
| Group A | 13/11/2022 | Santa Fe | - | Atlético Junior | 0:0 | ||||
| Group A | 23/11/2022 | Atlético Junior | - | Santa Fe | 2:3 | ||||
| Group A | 28/11/2022 | Deportivo Pereira | - | Santa Fe | 5:1 | ||||
| Group A | 01/12/2022 | Santa Fe | - | Millonarios | 1:1 | |
Colombia