1. Round | 01/08/2021 | Real Estelí FC | - | H&H Export Sébaco | 4:0 | ||||
3. Round | 15/08/2021 | H&H Export Sébaco | - | Club Deportivo Ocotal | 0:1 | ||||
9. Round | 26/09/2021 | Real Madriz | - | H&H Export Sébaco | 3:3 | ||||
14. Round | 23/10/2021 | H&H Export Sébaco | - | Juventus Managua | 3:3 |