| 1. Round | 02/04/2022 | Deportivo Coopsol | - | Los Chankas | 2:0 |  |
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| 2. Round | 10/04/2022 | Santos FC | - | Deportivo Coopsol | 2:2 | ||||
| 4. Round | 23/04/2022 | Deportivo Coopsol | - | Unión Huaral | 0:1 | ||||
| 8. Round | 21/05/2022 | Deportivo Coopsol | - | Unión Comercio | 0:1 | ||||
| 9. Round | 28/05/2022 | Cusco FC | - | Deportivo Coopsol | 3:0 | ||||
| 10. Round | 04/06/2022 | Deportivo Coopsol | - | Alfonso Ugarte | 2:1 | ||||
| 11. Round | 12/06/2022 | Chavelines Juniors | - | Deportivo Coopsol | 0:0 | ||||
| 12. Round | 18/06/2022 | Deportivo Coopsol | - | Pirata | 1:1 | ||||
| 13. Round | 26/06/2022 | Llacuabamba | - | Deportivo Coopsol | 2:1 |
Colombia