| 1. Round | 21/08/2022 | Valletta FC | - | Hibernians FC | 1:1 | ||||
| 2. Round | 26/08/2022 | Pietá Hotspurs | - | Valletta FC | 0:6 | ||||
| 8. Round | 22/10/2022 | Valletta FC | - | Gżira United | 0:0 |  |
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| 9. Round | 29/10/2022 | Balzan FC | - | Valletta FC | 1:3 | ||||
| 10. Round | 06/11/2022 | Valletta FC | - | Żebbuġ Rangers | 3:0 | ||||
| 11. Round | 12/11/2022 | St. Luċija FC | - | Valletta FC | 0:2 | ||||
| 12. Round | 04/12/2022 | Valletta FC | - | Gudja United | 0:1 | ||||
| 14. Round | 17/12/2022 | Hibernians FC | - | Valletta FC | 0:4 | ||||
| 15. Round | 08/01/2023 | Valletta FC | - | Pietá Hotspurs | 1:1 | ||||
| 16. Round | 01/02/2023 | Sirens FC | - | Valletta FC | 3:3 | ||||
| 18. Round | 05/02/2023 | Valletta FC | - | Birkirkara FC | 1:1 | |
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| 19. Round | 11/02/2023 | Hamrun Spartans | - | Valletta FC | 1:0 | |
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| 21. Round | 05/03/2023 | Gżira United | - | Valletta FC | 1:2 | ||||
| 23. Round | 01/04/2023 | Żebbuġ Rangers | - | Valletta FC | 1:5 | ||||
| 25. Round | 14/04/2023 | Gudja United | - | Valletta FC | 1:2 | ||||
| 26. Round | 20/04/2023 | Valletta FC | - | Marsaxlokk FC | 1:1 |
Nigeria