| 1. Round | 30/04/2022 | Villa Española | - | Rampla Juniors | 3:2 |  |
|||
| 3. Round | 15/05/2022 | Racing | - | Rampla Juniors | 1:0 | ||||
| 5. Round | 25/05/2022 | Rampla Juniors | - | Progreso | 1:1 |  |
|||
| 7. Round | 05/06/2022 | Rampla Juniors | - | Atenas | 0:3 | |
|||
| 9. Round | 18/06/2022 | Rampla Juniors | - | Sud América | 0:0 | ||||
| 16. Round | 20/08/2022 | Progreso | - | Rampla Juniors | 0:1 |
Colombia