| 5. Round | 15/09/2021 | HNK Cibalia | - | NK Sesvete | 0:1 | ||||
| 7. Round | 25/09/2021 | NK Kustošija | - | NK Sesvete | 1:2 |  |
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| 8. Round | 01/10/2021 | NK Sesvete | - | NK BSK Bijelo Brdo | 0:1 | |
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| 9. Round | 17/10/2021 | Dinamo Zagreb II | - | NK Sesvete | 2:1 | ||||
| 10. Round | 22/10/2021 | NK Sesvete | - | NK Solin | 4:0 |  |
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| 11. Round | 31/10/2021 | NK Croatia Zmijavci | - | NK Sesvete | 1:0 | |
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| 13. Round | 20/11/2021 | NK Varaždin | - | NK Sesvete | 2:1 | |
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| 14. Round | 26/11/2021 | NK Sesvete | - | NK Rudeš | 0:0 | ||||
| 15. Round | 04/12/2021 | NK Jarun | - | NK Sesvete | 4:3 | |
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| 17. Round | 19/02/2022 | NK Dugopolje | - | NK Sesvete | 2:1 | |
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| 22. Round | 01/04/2022 | NK Sesvete | - | NK Kustošija | 0:2 | ||||
| 23. Round | 10/04/2022 | NK BSK Bijelo Brdo | - | NK Sesvete | 0:0 | ||||
| 24. Round | 15/04/2022 | NK Sesvete | - | Dinamo Zagreb II | 4:0 | |
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| 25. Round | 23/04/2022 | NK Solin | - | NK Sesvete | 4:0 | ||||
| 26. Round | 01/05/2022 | NK Sesvete | - | NK Croatia Zmijavci | 2:2 |
Croatia