| 1. Round | 30/07/2000 | Hrvatski Dragovoljac | - | NK Čakovec | 2:0 |  |
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| 2. Round | 05/08/2000 | NK Čakovec | - | NK Varteks | 2:2 |  |
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| 4. Round | 19/08/2000 | NK Čakovec | - | Hajduk Split | 2:0 | ||||
| 5. Round | 27/08/2000 | NK Marsonia | - | NK Čakovec | 0:1 | ||||
| 6. Round | 09/09/2000 | NK Čakovec | - | NK Zagreb | 1:1 | ||||
| 7. Round | 16/09/2000 | Slaven Belupo | - | NK Čakovec | 0:0 | ||||
| 8. Round | 24/09/2000 | HNK Šibenik | - | NK Čakovec | 3:0 | ||||
| 9. Round | 30/09/2000 | NK Čakovec | - | HNK Cibalia | 1:0 | |
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| 10. Round | 04/10/2000 | HNK Rijeka | - | NK Čakovec | 1:1 |  |
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| 11. Round | 14/10/2000 | NK Čakovec | - | Dinamo Zagreb | 0:0 | |
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| 13. Round | 28/10/2000 | NK Varteks | - | NK Čakovec | 1:0 | |
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| 15. Round | 12/11/2000 | Hajduk Split | - | NK Čakovec | 3:1 | ||||
| 17. Round | 26/11/2000 | NK Zagreb | - | NK Čakovec | 3:0 | |
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| 18. Round | 02/12/2000 | NK Čakovec | - | Slaven Belupo | 0:0 | ||||
| 19. Round | 25/02/2001 | NK Čakovec | - | HNK Šibenik | 1:0 | |
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| 20. Round | 04/03/2001 | HNK Cibalia | - | NK Čakovec | 3:2 | ||||
| 21. Round | 11/03/2001 | NK Čakovec | - | HNK Rijeka | 1:0 | ||||
| 22. Round | 18/03/2001 | Dinamo Zagreb | - | NK Čakovec | 3:0 |
Croatia