| 1. Round | 03/02/2019 | Boca Juniors de Cali | - | Real San Andrés | 1:1 | ||||
| 2. Round | 11/02/2019 | Deportivo Pereira | - | Real San Andrés | 1:0 | ||||
| 3. Round | 17/02/2019 | Real San Andrés | - | Orsomarso SC | 2:2 |  |
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| 4. Round | 21/02/2019 | Valledupar FC | - | Real San Andrés | 2:0 | ||||
| 5. Round | 24/02/2019 | Real San Andrés | - | Tigres FC | 1:1 | ||||
| 6. Round | 03/03/2019 | Atlético FC | - | Real San Andrés | 0:1 | ||||
| 7. Round | 10/03/2019 | Real San Andrés | - | Deportes Quindío | 1:1 | ||||
| 8. Round | 16/03/2019 | Barranquilla FC | - | Real San Andrés | 2:0 | ||||
| 9. Round | 24/03/2019 | Real San Andrés | - | Fortaleza FC | 2:2 |  |
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Colombia