| 1. Round | 05/02/2025 | Deportes Quindío | - | Atlético Huila | 1:0 | ||||
| 2. Round | 10/02/2025 | Boca Juniors de Cali | - | Deportes Quindío | 4:0 | ||||
| 6. Round | 09/03/2025 | Deportes Quindío | - | Patriotas FC | 0:1 |  |
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| 9. Round | 27/03/2025 | Atlético Huila | - | Deportes Quindío | 2:0 | ||||
| 10. Round | 06/04/2025 | Leones FC | - | Deportes Quindío | 4:1 | ||||
| 11. Round | 12/04/2025 | Deportes Quindío | - | Real Soacha Cundinamarca | 0:0 | ||||
| 12. Round | 19/04/2025 | Bogotá FC | - | Deportes Quindío | 1:1 | ||||
| 5. Round | 24/04/2025 | Barranquilla FC | - | Deportes Quindío | 1:1 |  |
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| 13. Round | 27/04/2025 | Deportes Quindío | - | Real Santander | 4:2 | |
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Colombia