| 1. Round | 25/07/2021 | Tigres FC | - | Bogotá FC | 0:0 | ||||
| 2. Round | 01/08/2021 | Bogotá FC | - | Barranquilla FC | 2:0 | ||||
| 8. Round | 15/09/2021 | Fortaleza FC | - | Bogotá FC | 3:0 | ||||
| 10. Round | 26/09/2021 | Cortuluá | - | Bogotá FC | 0:0 | ||||
| 11. Round | 01/10/2021 | Bogotá FC | - | Unión Magdalena | 3:1 | ||||
| 12. Round | 08/10/2021 | Boca Juniors de Cali | - | Bogotá FC | 1:2 | ||||
| 14. Round | 24/10/2021 | Leones FC | - | Bogotá FC | 1:0 |
Colombia