| 7. Round | 18/02/2021 | Millonarios | - | Deportivo Pasto | 3:1 | ||||
| 2. Round | 04/03/2021 | Boyacá Chicó | - | Millonarios | 0:1 | ||||
| 12. Round | 14/03/2021 | Patriotas FC | - | Millonarios | 0:2 | ||||
| 13. Round | 22/03/2021 | Millonarios | - | Atlético Nacional | 1:2 | ||||
| 16. Round | 31/03/2021 | América de Cali | - | Millonarios | 2:1 |  |
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| 17. Round | 04/04/2021 | Millonarios | - | Deportes Tolima | 0:0 | ||||
| 18. Round | 12/04/2021 | Santa Fe | - | Millonarios | 1:2 |
Colombia