| 2. Round | 31/07/2022 | Veraguas United | - | Herrera FC | 0:0 | ||||
| 3. Round | 07/08/2022 | Herrera FC | - | Independiente de La Chorrera | 0:5 | ||||
| 4. Round | 10/08/2022 | Herrera FC | - | UD Universitario | 2:2 | ||||
| 5. Round | 13/08/2022 | San Francisco FC | - | Herrera FC | 5:0 | ||||
| 1. Round | 18/08/2022 | Atlético Chiriquí | - | Herrera FC | 0:0 |  |
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| 6. Round | 21/08/2022 | Tauro FC | - | Herrera FC | 2:1 | ||||
| 7. Round | 28/08/2022 | Herrera FC | - | Sporting San Miguelito | 0:0 | ||||
| 8. Round | 04/09/2022 | Alianza | - | Herrera FC | 1:1 | ||||
| 9. Round | 10/09/2022 | Herrera FC | - | Plaza Amador | 0:1 | ||||
| 10. Round | 17/09/2022 | Potros del Este | - | Herrera FC | 4:0 | ||||
| 11. Round | 25/09/2022 | Herrera FC | - | Árabe Unido | 2:1 | |
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| 12. Round | 27/09/2022 | Herrera FC | - | Atlético Chiriquí | 0:0 | ||||
| 15. Round | 16/10/2022 | UD Universitario | - | Herrera FC | 2:0 | ||||
| 16. Round | 23/10/2022 | Herrera FC | - | San Francisco FC | 0:2 | |
Panama