| 4. Round | 27/02/2022 | Alianza Atlético | - | Alianza Lima | 4:2 | ||||
| 6. Round | 12/03/2022 | Alianza Atlético | - | Universidad San Martín | 3:1 | ||||
| 8. Round | 02/04/2022 | Alianza Atlético | - | Deportivo Municipal | 2:2 |  |
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| 9. Round | 10/04/2022 | Cienciano | - | Alianza Atlético | 5:0 | |
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| 10. Round | 15/04/2022 | Alianza Atlético | - | Deportivo Binacional | 2:0 | ||||
| 11. Round | 24/04/2022 | AD Tarma | - | Alianza Atlético | 1:2 | ||||
| 12. Round | 01/05/2022 | Alianza Atlético | - | Ayacucho FC | 2:1 | ||||
| 13. Round | 07/05/2022 | Universitario de Deportes | - | Alianza Atlético | 3:1 | ||||
| 14. Round | 15/05/2022 | Alianza Atlético | - | Sport Boys | 1:2 | |
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| 15. Round | 22/05/2022 | Atlético Grau | - | Alianza Atlético | 1:2 | ||||
| 17. Round | 19/06/2022 | Alianza Atlético | - | Mannucci | 0:0 |  |
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| 19. Round | 03/07/2022 | Alianza Atlético | - | FBC Melgar | 0:0 | |
Peru