| 1. Round | 16/01/2021 | Orsomarso SC | - | Barranquilla FC | 2:2 |  |
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| 2. Round | 22/01/2021 | Barranquilla FC | - | Boca Juniors de Cali | 0:1 | ||||
| 3. Round | 01/02/2021 | Real Cartagena | - | Barranquilla FC | 1:0 | ||||
| 4. Round | 06/02/2021 | Barranquilla FC | - | Real Santander | 1:0 | ||||
| 5. Round | 11/02/2021 | Bogotá FC | - | Barranquilla FC | 1:0 | |
Colombia