| 1. Round | 21/07/2022 | Puntarenas FC | - | AD San Carlos | 3:0 | ||||
| 2. Round | 25/07/2022 | AD San Carlos | - | Municipal Pérez Zeledón | 2:1 | ||||
| 3. Round | 31/07/2022 | AD San Carlos | - | CS Cartaginés | 1:1 | ||||
| 4. Round | 07/08/2022 | Municipal Grecia | - | AD San Carlos | 0:1 | ||||
| 5. Round | 11/08/2022 | AD San Carlos | - | Deportivo Saprissa | 2:1 | ||||
| 6. Round | 15/08/2022 | Deportivo Saprissa | - | AD San Carlos | 3:0 |  |
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| 8. Round | 28/08/2022 | Municipal Pérez Zeledón | - | AD San Carlos | 0:2 | ||||
| 9. Round | 01/09/2022 | AD San Carlos | - | Puntarenas FC | 2:2 |  |
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| 10. Round | 04/09/2022 | CS Cartaginés | - | AD San Carlos | 3:2 | ||||
| 11. Round | 11/09/2022 | AD San Carlos | - | AD Guanacasteca | 1:0 | |
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| 12. Round | 18/09/2022 | AD San Carlos | - | Santos de Guápiles | 1:1 | ||||
| 13. Round | 22/09/2022 | Guadalupe | - | AD San Carlos | 2:1 | ||||
| 14. Round | 25/09/2022 | AD San Carlos | - | LD Alajuelense | 0:0 | ||||
| 15. Round | 30/09/2022 | Sporting FC | - | AD San Carlos | 2:1 | ||||
| 16. Round | 02/10/2022 | CS Herediano | - | AD San Carlos | 2:2 | |
Costa Rica
Nicaragua