| 7. Round | 01/03/2020 | Alianza Petrolera | - | Deportes Tolima | 0:1 |  |
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| 8. Round | 09/03/2020 | Deportes Tolima | - | Patriotas FC | 1:0 | ||||
| 11. Round | 04/10/2020 | Deportivo Pereira | - | Deportes Tolima | 0:0 | ||||
| 13. Round | 11/10/2020 | Cúcuta Deportivo | - | Deportes Tolima | 0:3 | ||||
| 14. Round | 15/10/2020 | Deportes Tolima | - | Alianza Petrolera | 3:1 | ||||
| 15. Round | 18/10/2020 | Jaguares de Córdoba | - | Deportes Tolima | 1:1 | ||||
| 16. Round | 25/10/2020 | Deportes Tolima | - | La Equidad | 1:2 | |
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| 18. Round | 07/11/2020 | Deportes Tolima | - | Boyacá Chicó | 2:0 | |
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| 19. Round | 11/11/2020 | Santa Fe | - | Deportes Tolima | 1:0 | ||||
| 20. Round | 15/11/2020 | Deportes Tolima | - | Once Caldas | 2:3 |
Colombia