| 9. Round | 26/09/2009 | Sporting Lokeren | - | Sporting Charleroi | 4:1 | ||||
| 10. Round | 03/10/2009 | KV Mechelen | - | Sporting Lokeren | 2:0 | ||||
| 12. Round | 23/10/2009 | Sporting Lokeren | - | KRC Genk | 0:2 |  |
|||
| 13. Round | 31/10/2009 | RSC Anderlecht | - | Sporting Lokeren | 2:0 | ||||
| 14. Round | 07/11/2009 | Sporting Lokeren | - | KV Kortrijk | 0:0 | ||||
| 15. Round | 21/11/2009 | KVC Westerlo | - | Sporting Lokeren | 1:0 | ||||
| 16. Round | 29/11/2009 | SV Zulte Waregem | - | Sporting Lokeren | 1:0 | |
|||
| 17. Round | 06/12/2009 | Sporting Lokeren | - | Club Brugge KV | 0:1 | ||||
| 18. Round | 12/12/2009 | Excelsior Mouscron | - | Sporting Lokeren | annull. | ||||
| 19. Round | 19/12/2009 | Sporting Lokeren | - | KAA Gent | 0:1 | ||||
| 20. Round | 26/12/2009 | Standard Liège | - | Sporting Lokeren | 2:0 | ||||
| 21. Round | 30/12/2009 | Sporting Lokeren | - | Germinal Beerschot | 2:0 | ||||
| 22. Round | 16/01/2010 | Sint-Truidense VV | - | Sporting Lokeren | 2:1 | |
|||
| 23. Round | 23/01/2010 | Sporting Lokeren | - | KSV Roeselare | 1:4 | ||||
| 27. Round | 19/02/2010 | KRC Genk | - | Sporting Lokeren | 3:1 | ||||
| 28. Round | 27/02/2010 | Sporting Lokeren | - | KVC Westerlo | 1:0 | |
Serbia