| 1. Round | 19/05/2019 | Sport Loreto | - | Santos FC | 0:1 | ||||
| 2. Round | 26/05/2019 | Santos FC | - | Atlético Grau | 2:0 | ||||
| 3. Round | 01/06/2019 | Juan Aurich | - | Santos FC | 2:1 | ||||
| 4. Round | 09/06/2019 | Santos FC | - | Sport Victoria | 1:0 | ||||
| 5. Round | 16/06/2019 | Santos FC | - | Deportivo Coopsol | 1:1 | ||||
| 6. Round | 14/07/2019 | Cultural Santa Rosa | - | Santos FC | 0:1 | ||||
| 7. Round | 21/07/2019 | Santos FC | - | Comerciantes Unidos | 2:0 | ||||
| 8. Round | 28/07/2019 | Alianza Atlético | - | Santos FC | 3:0 dec. | ||||
| 9. Round | 04/08/2019 | Santos FC | - | Los Caimanes | 1:0 | ||||
| 12. Round | 01/09/2019 | Santos FC | - | Sport Loreto | 3:0 | ||||
| 13. Round | 08/09/2019 | Atlético Grau | - | Santos FC | 3:0 dec. | ||||
| 14. Round | 15/09/2019 | Santos FC | - | Juan Aurich | 0:2 | ||||
| 16. Round | 29/09/2019 | Deportivo Coopsol | - | Santos FC | 1:2 | ||||
| 17. Round | 05/10/2019 | Santos FC | - | Cultural Santa Rosa | 2:0 | ||||
| 18. Round | 13/10/2019 | Comerciantes Unidos | - | Santos FC | 3:0 | ||||
| 19. Round | 20/10/2019 | Santos FC | - | Alianza Atlético | 1:1 | ||||
| 20. Round | 26/10/2019 | Los Caimanes | - | Santos FC | 0:0 | ||||
| 21. Round | 03/11/2019 | Santos FC | - | Unión Huaral | 2:1 | ||||
| 22. Round | 10/11/2019 | Cienciano | - | Santos FC | 4:2 |
Peru