| 1. Round | 13/09/2020 | Adanaspor | - | İstanbulspor AŞ | 1:0 | ||||
| 2. Round | 20/09/2020 | İstanbulspor AŞ | - | Altay Izmir | 2:1 |  |
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| 3. Round | 26/09/2020 | Ümraniyespor | - | İstanbulspor AŞ | 1:3 | ||||
| 4. Round | 02/10/2020 | İstanbulspor AŞ | - | Bandırmaspor | 2:1 | ||||
| 5. Round | 17/10/2020 | Samsunspor | - | İstanbulspor AŞ | 0:3 | |
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| 6. Round | 22/10/2020 | İstanbulspor AŞ | - | Akhisar Belediyespor | 2:2 | ||||
| 7. Round | 25/10/2020 | İstanbulspor AŞ | - | Eskişehirspor | 3:0 | ||||
| 8. Round | 01/11/2020 | Keçiörengücü | - | İstanbulspor AŞ | 1:1 |  |
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| 10. Round | 21/11/2020 | Altınordu FK | - | İstanbulspor AŞ | 1:0 | ||||
| 12. Round | 04/12/2020 | Tuzlaspor | - | İstanbulspor AŞ | 2:0 | |
Ghana