| 11. Round | 06/11/2021 | FC Barcelona B | - | Sevilla Atlético | 4:0 | ||||
| 14. Round | 27/11/2021 | FC Barcelona B | - | San Fernando CD | 0:2 |  |
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| 15. Round | 05/12/2021 | Villarreal CF B | - | FC Barcelona B | 3:0 | ||||
| 17. Round | 19/12/2021 | UE Cornellà | - | FC Barcelona B | 1:0 | ||||
| 19. Round | 22/01/2022 | FC Barcelona B | - | UCAM Murcia CF | 2:2 | ||||
| 20. Round | 25/01/2022 | UE Costa Brava | - | FC Barcelona B | 2:2 | ||||
| 21. Round | 29/01/2022 | FC Barcelona B | - | Real Madrid Castilla | 2:2 | |
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| 22. Round | 05/02/2022 | Algeciras CF | - | FC Barcelona B | 2:1 | |
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| 24. Round | 20/02/2022 | FC Barcelona B | - | Albacete | 2:2 | |
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| 26. Round | 05/03/2022 | FC Barcelona B | - | Gimnàstic de Tarragona | 0:2 | ||||
| 27. Round | 12/03/2022 | FC Andorra | - | FC Barcelona B | 2:1 |
France
Morocco