| 4. Round | 28/08/2021 | Angers SCO B | - | Canet Roussillon | 2:0 |  |
|||
| 5. Round | 03/09/2021 | Angoulême CFC | - | Angers SCO B | 4:0 | ||||
| 13. Round | 04/12/2021 | Angers SCO B | - | Vendée Les Herbiers | 2:2 | ||||
| 14. Round | 11/12/2021 | Montpellier HSC B | - | Angers SCO B | 0:4 | ||||
| 15. Round | 15/01/2022 | Angers SCO B | - | FC Chamalières | 1:1 | ||||
| 16. Round | 22/01/2022 | US Colomiers | - | Angers SCO B | 0:0 | ||||
| 18. Round | 12/02/2022 | Canet Roussillon | - | Angers SCO B | 2:0 | ||||
| 20. Round | 05/03/2022 | Trélissac FC | - | Angers SCO B | 1:1 | ||||
| 22. Round | 19/03/2022 | AS Béziers | - | Angers SCO B | 1:1 | ||||
| 23. Round | 26/03/2022 | Angers SCO B | - | Stade Montois | 0:0 | ||||
| 24. Round | 09/04/2022 | Bourges Foot 18 | - | Angers SCO B | 0:1 | ||||
| 25. Round | 16/04/2022 | Angers SCO B | - | Le Puy Foot 43 | 0:2 | ||||
| 27. Round | 29/04/2022 | Vendée Les Herbiers | - | Angers SCO B | 1:1 | |
|||
| 28. Round | 14/05/2022 | Angers SCO B | - | Montpellier HSC B | 1:0 | ||||
| 29. Round | 21/05/2022 | FC Chamalières | - | Angers SCO B | 1:0 |
France
Congo