| Primera | 24/01/21 | Real Madriz | - | CD Walter Ferretti | 1:1 |  |
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| Primera | 03/02/21 | Managua FC | - | Real Madriz | 4:1 | ||||
| Primera | 14/03/21 | Real Madriz | - | Diriangén FC | 1:2 |  |
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| Primera | 10/05/21 | Managua FC | - | Real Madriz | 1:0 | ||||
| Primera | 16/08/21 | Real Madriz | - | Juventus Managua | 2:0 | ||||
| Primera | 01/11/21 | ART Municipal Jalapa | - | Real Madriz | 0:1 | ||||
| Primera | 07/03/22 | Real Madriz | - | Managua FC | 1:0 | |
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| Primera | 01/05/22 | Real Madriz | - | H&H Export Sébaco | 0:0 |
Nicaragua