| 1. Round | 22/07/2024 | Leones FC | - | Real Santander | 2:0 | ||||
| 2. Round | 29/07/2024 | Real Santander | - | Real Soacha Cundinamarca | 0:1 | ||||
| 3. Round | 04/08/2024 | Tigres FC | - | Real Santander | 1:0 | ||||
| 4. Round | 10/08/2024 | Real Santander | - | Deportes Quindío | 0:2 | ||||
| 5. Round | 16/08/2024 | Atlético FC | - | Real Santander | 0:1 | ||||
| 6. Round | 21/08/2024 | Real Santander | - | Barranquilla FC | 2:1 | ||||
| 8. Round | 31/08/2024 | Unión Magdalena | - | Real Santander | 4:0 | ||||
| 9. Round | 09/10/2024 | Real Santander | - | Cúcuta Deportivo | 0:2 | ||||
| 15. Round | 16/10/2024 | Real Santander | - | Llaneros FC | 0:4 | ||||
| 16. Round | 23/10/2024 | Internacional de Palmira | - | Real Santander | 4:2 |
Colombia