| 1. Round | 22/08/2021 | Moroka Swallows | - | Royal AM | 1:0 | ||||
| 2. Round | 25/08/2021 | AmaZulu FC | - | Moroka Swallows | 0:0 | ||||
| 3. Round | 11/09/2021 | Orlando Pirates | - | Moroka Swallows | 1:0 | ||||
| 5. Round | 24/09/2021 | Moroka Swallows | - | Cape Town City FC | 0:0 | ||||
| 6. Round | 03/10/2021 | Mamelodi Sundowns | - | Moroka Swallows | 3:0 | ||||
| 7. Round | 17/10/2021 | Moroka Swallows | - | Stellenbosch FC | 1:1 | ||||
| 11. Round | 21/11/2021 | TS Galaxy | - | Moroka Swallows | 1:0 | ||||
| 12. Round | 28/11/2021 | Moroka Swallows | - | Kaizer Chiefs | 1:3 | ||||
| 22. Round | 14/12/2021 | Moroka Swallows | - | Orlando Pirates | 1:1 | ||||
| 18. Round | 16/02/2022 | Stellenbosch FC | - | Moroka Swallows | 1:1 | ||||
| 19. Round | 19/02/2022 | Moroka Swallows | - | TS Galaxy | 0:1 | ||||
| 20. Round | 26/02/2022 | Sekhukhune United | - | Moroka Swallows | 0:1 | ||||
| 21. Round | 06/03/2022 | Royal AM | - | Moroka Swallows | 1:0 |  |
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| 24. Round | 06/04/2022 | Moroka Swallows | - | Mamelodi Sundowns | 2:4 | ||||
| 26. Round | 24/04/2022 | Moroka Swallows | - | Baroka FC | 3:2 | ||||
| 27. Round | 03/05/2022 | Moroka Swallows | - | AmaZulu FC | 0:1 | ||||
| 30. Round | 21/05/2022 | Kaizer Chiefs | - | Moroka Swallows | 2:2 |
South Africa