| 3. Round | 25/09/2020 | Aston Villa U23 | - | Reading FC U23 | 1:2 | ||||
| 4. Round | 02/10/2020 | West Bromwich Albion U23 | - | Reading FC U23 | 1:1 | ||||
| 15. Round | 22/01/2021 | Fulham FC U23 | - | Reading FC U23 | 0:3 | ||||
| 16. Round | 29/01/2021 | Reading FC U23 | - | Aston Villa U23 | 3:1 |  |
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| 17. Round | 05/02/2021 | Reading FC U23 | - | West Bromwich Albion U23 | 5:2 | ||||
| 18. Round | 15/02/2021 | Leeds United U23 | - | Reading FC U23 | 3:0 | ||||
| 20. Round | 01/03/2021 | Newcastle United U23 | - | Reading FC U23 | 1:2 | ||||
| 14. Round | 05/03/2021 | Reading FC U23 | - | Norwich City U23 | 1:3 | ||||
| 21. Round | 12/03/2021 | Reading FC U23 | - | Crystal Palace U23 | 2:1 | |
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| 12. Round | 02/04/2021 | Reading FC U23 | - | Sunderland AFC U23 | 0:2 | ||||
| 23. Round | 09/04/2021 | Reading FC U23 | - | Middlesbrough FC U23 | 2:4 | ||||
| 24. Round | 16/04/2021 | Reading FC U23 | - | Burnley FC U23 | 0:2 | ||||
| 25. Round | 26/04/2021 | Sunderland AFC U23 | - | Reading FC U23 | 2:1 | ||||
| 26. Round | 30/04/2021 | Reading FC U23 | - | Wolverhampton Wanderers U23 | 5:0 | ||||
| 13. Round | 10/05/2021 | Wolverhampton Wanderers U23 | - | Reading FC U23 | 2:2 |
Ireland