| 1. Round | 28/08/2022 | APOEL Nikosia | - | Paphos FC | 1:1 | ||||
| 7. Round | 16/10/2022 | Akritas Chlorakas | - | APOEL Nikosia | 1:2 | ||||
| 8. Round | 22/10/2022 | APOEL Nikosia | - | AEK Larnaca | 1:0 | ||||
| 9. Round | 30/10/2022 | Apollon Limassol | - | APOEL Nikosia | 0:1 | ||||
| 10. Round | 04/11/2022 | APOEL Nikosia | - | Enosis Neon Paralimni | 2:0 | ||||
| 11. Round | 13/11/2022 | Doxa Katokopias | - | APOEL Nikosia | 0:1 | ||||
| 12. Round | 27/11/2022 | APOEL Nikosia | - | Omonia Nikosia | 4:0 |  |
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| 13. Round | 03/12/2022 | Nea Salamina | - | APOEL Nikosia | 1:3 |  |
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| 14. Round | 09/12/2022 | Paphos FC | - | APOEL Nikosia | 1:2 | ||||
| 15. Round | 17/12/2022 | APOEL Nikosia | - | Anorthosis Famagusta | 1:0 | ||||
| 16. Round | 22/12/2022 | Aris Limassol | - | APOEL Nikosia | 1:1 | ||||
| 19. Round | 14/01/2023 | Karmiotissa Polemidion | - | APOEL Nikosia | 1:2 | ||||
| 20. Round | 22/01/2023 | APOEL Nikosia | - | Akritas Chlorakas | 2:0 | ||||
| 21. Round | 28/01/2023 | AEK Larnaca | - | APOEL Nikosia | 2:1 | ||||
| 24. Round | 19/02/2023 | APOEL Nikosia | - | Doxa Katokopias | 1:1 | |
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| 25. Round | 25/02/2023 | Omonia Nikosia | - | APOEL Nikosia | 0:2 | ||||
| 26. Round | 06/03/2023 | APOEL Nikosia | - | Nea Salamina | 3:0 |
Georgia