| 1. Round | 20/07/2019 | FK Senica | - | AS Trenčín | 3:1 | ||||
| 2. Round | 27/07/2019 | ŠKF Sereď | - | FK Senica | 2:1 | ||||
| 3. Round | 03/08/2019 | FK Senica | - | Slovan Bratislava | 0:3 |  |
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| 4. Round | 10/08/2019 | MFK Zemplín Michalovce | - | FK Senica | 3:0 | |
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| 9. Round | 18/09/2019 | Spartak Trnava | - | FK Senica | 0:0 | |
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| 10. Round | 28/09/2019 | FK Senica | - | FK Pohronie | 1:0 | ||||
| 11. Round | 05/10/2019 | FC Nitra | - | FK Senica | 1:4 | ||||
| 12. Round | 20/10/2019 | AS Trenčín | - | FK Senica | 2:3 | ||||
| 13. Round | 26/10/2019 | FK Senica | - | ŠKF Sereď | 0:1 | |
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| 15. Round | 09/11/2019 | FK Senica | - | MFK Zemplín Michalovce | 4:0 | ||||
| 16. Round | 23/11/2019 | MFK Ružomberok | - | FK Senica | 2:2 | ||||
| 17. Round | 30/11/2019 | Zlaté Moravce | - | FK Senica | 0:0 | ||||
| 18. Round | 08/12/2019 | FK Senica | - | MŠK Žilina | 1:2 |
Croatia