| 1. Round | 19/09/2021 | SP Tre Penne | - | SS Virtus | 2:0 | ||||
| 2. Round | 24/09/2021 | SS Virtus | - | SS Cosmos | 2:0 | ||||
| 6. Round | 23/10/2021 | SS Virtus | - | SP La Fiorita | 0:0 | ||||
| 7. Round | 31/10/2021 | SS Virtus | - | SS Folgore/Falciano | 1:0 | ||||
| 9. Round | 21/11/2021 | SS Virtus | - | AC Libertas | 0:1 | ||||
| 10. Round | 28/11/2021 | AC Juvenes/Dogana | - | SS Virtus | 1:2 | ||||
| 11. Round | 04/12/2021 | SS Virtus | - | FC Fiorentino | 2:1 | ||||
| 18. Round | 29/01/2022 | SS Virtus | - | SC Faetano | 0:0 | ||||
| 19. Round | 06/02/2022 | FC Domagnano | - | SS Virtus | 0:0 | ||||
| 29. Round | 14/04/2022 | SP Tre Fiori | - | SS Virtus | 1:0 | ||||
| 30. Round | 21/04/2022 | SS Virtus | - | SS Murata | 1:0 |
Italy