| 6. Round | 02/05/2021 | Bolívar | - | Real Tomayapo | 2:0 | ||||
| 7. Round | 08/05/2021 | Club San José | - | Bolívar | 0:5 | ||||
| 8. Round | 12/07/2021 | Bolívar | - | Real Santa Cruz | 1:1 | ||||
| 27. Round | 28/11/2021 | Jorge Wilstermann | - | Bolívar | 1:0 | ||||
| 28. Round | 01/12/2021 | Bolívar | - | Atlético Palmaflor | 3:1 | ||||
| 29. Round | 05/12/2021 | Always Ready | - | Bolívar | 1:1 |
Bolivia