| 1. Round | 20/07/2018 | Alianza Petrolera | - | La Equidad | 0:2 |  |
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| 2. Round | 31/07/2018 | Leones FC | - | Alianza Petrolera | 0:1 | ||||
| 3. Round | 06/08/2018 | Alianza Petrolera | - | Deportes Tolima | 4:2 | |
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| 4. Round | 12/08/2018 | Santa Fe | - | Alianza Petrolera | 4:0 | ||||
| 7. Round | 02/09/2018 | Alianza Petrolera | - | América de Cali | 2:2 | ||||
| 8. Round | 05/09/2018 | Alianza Petrolera | - | Millonarios | 3:2 | ||||
| 9. Round | 08/09/2018 | Jaguares de Córdoba | - | Alianza Petrolera | 1:0 | ||||
| 10. Round | 17/09/2018 | Alianza Petrolera | - | Atlético Bucaramanga | 1:2 | ||||
| 11. Round | 23/09/2018 | Deportivo Pasto | - | Alianza Petrolera | 2:1 | ||||
| 12. Round | 30/09/2018 | Alianza Petrolera | - | Envigado FC | 1:2 | ||||
| 14. Round | 13/10/2018 | Alianza Petrolera | - | Boyacá Chicó | 1:0 | ||||
| 15. Round | 18/10/2018 | Independiente Medellín | - | Alianza Petrolera | 2:0 | ||||
| 16. Round | 22/10/2018 | Alianza Petrolera | - | Deportivo Cali | 2:0 | ||||
| 17. Round | 28/10/2018 | Águilas Doradas | - | Alianza Petrolera | 1:0 | |
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| 18. Round | 06/11/2018 | Alianza Petrolera | - | Atlético Junior | 0:3 | |
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| 19. Round | 10/11/2018 | Once Caldas | - | Alianza Petrolera | 1:0 |
Colombia