| 3. Round | 27/04/2023 | Tampa Bay Rowdies | - | Houston Dynamo | 0:1 | ||||
| 4. Round | 11/05/2023 | Houston Dynamo | - | Sporting Kansas City | 1:0 | ||||
| Round of 16 | 24/05/2023 | Houston Dynamo | - | Minnesota United FC | 4:0 |  |
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| Quarter-finals | 07/06/2023 | Chicago Fire | - | Houston Dynamo | 1:4 | ||||
| Semi-finals | 24/08/2023 | Houston Dynamo | - | Real Salt Lake | 3:1 aet |  |
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| Final | 28/09/2023 | Inter Miami CF | - | Houston Dynamo | 1:2 |
Colombia