| 2. Round | 07/10/2020 | Marathón | - | Motagua | 1:2 | ||||
| 3. Round | 11/10/2020 | Vida | - | Marathón | 0:1 |  |
|||
| 4. Round | 14/10/2020 | Marathón | - | Real España | 3:0 | ||||
| 5. Round | 18/10/2020 | Platense | - | Marathón | 0:1 | |
|||
| 7. Round | 25/10/2020 | Motagua | - | Marathón | 1:1 | |
|||
| 8. Round | 28/10/2020 | Marathón | - | Vida | 0:2 | ||||
| 9. Round | 02/11/2020 | Real España | - | Marathón | 0:1 | ||||
| 10. Round | 22/11/2020 | Marathón | - | Platense | 3:0 | ||||
| 11. Round | 25/11/2020 | Lobos UPNFM | - | Marathón | 0:2 | |
|||
| 6. Round | 05/12/2020 | Marathón | - | Honduras Progreso | 4:0 | ||||
| 14. Round | 12/12/2020 | Marathón | - | Olimpia | 1:3 |
Honduras