| 4. Round | 10/11/2021 | Metropolitanos FC | - | Hermanos Colmenarez | 1:0 |  |
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| 5. Round | 13/11/2021 | Aragua FC | - | Metropolitanos FC | 0:2 | |
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| 7. Round | 23/11/2021 | Portuguesa FC | - | Metropolitanos FC | 1:1 | ||||
| 8. Round | 28/11/2021 | Metropolitanos FC | - | Academia Puerto Cabello | 1:2 | ||||
| 9. Round | 30/11/2021 | Hermanos Colmenarez | - | Metropolitanos FC | 4:0 | ||||
| 10. Round | 04/12/2021 | Metropolitanos FC | - | Aragua FC | 2:2 | |
Venezuela